Grasshoppers thrive in thick grass or areas with lots of plant life, which makes them especially vulnerable to spiders, mantids and lizards. Birds often swoop down and feed on grasshoppers, and rodents also feed on grasshoppers.

In some parts of the world, humans catch grasshoppers to eat as protein. In the United States, educators and students catch grasshoppers to study in science classes.

When young, grasshoppers do not have wings, which makes them more vulnerable to predators. Grasshoppers rely on their strong legs and wings to escape predators. Adults with wings fly very fast. When in danger, they spit a brown liquid at predators.