Breeds of large dogs that don't shed include the Airedale Terrier, Standard Poodle, Bouvier des Flandres, Giant Schnauzer and Irish Water Spaniel. These breeds are considered hypoallergenic, which means they are safer for people who are prone to allergies.

Additional breeds include Komondor, Black Russian Terrier, Saluki, Wirehaired Pointing Griffon and Old English Sheepdog. Though these large dogs shed much less than other breeds, some have coarse, curly or long hair that needs periodic maintenance such as brushing and trimming. Irish Water Spaniels and Airedale Terriers, for instance, require frequent brushing, and the thick fur of standard poodles may need professional grooming. The coarse coat of the Komondor requires no brushing at all, as it divides naturally into dreadlocks that only need to be occasionally trimmed. Maintaining the coats of these large dogs by keeping them as short as possible minimizes painful and unsightly matting.

Allergies from dogs are mainly caused by dander, the dead skin that falls off dogs, rather than by their hair. Saliva, dander and dirt become trapped in the thick fur of these large dogs. Additionally, their fur is prone to picking up pollen from trees and flowers. Regular bathing helps to eliminate these problems. Other factors besides breed that influence hair loss in dogs include nutrition and overall good health. If a dog is healthy and well-fed, there is much less chance of shedding.