The average lifespan of Yorkshire terriers, including the teacup Yorkie, is 12 to 15 years. Where a regular Yorkshire terrier can weigh around 7 pounds as an adult, teacup Yorkies weigh only 2.5 pounds to 4 pounds as an adult.

All varieties of the Yorkshire terrier are susceptible to broken or fractured bones if they fall. Eye infections, bronchitis and tooth decay are also problems that plague this breed. Owners must take care to feed Yorkies a high-quality diet because of potential digestive issues that can lead to malnutrition. Even walking a teacup Yorkie takes special considerations. Because using a normal collar can lead to a collapsed windpipe, a harness is recommended.