Pet MD states that the average lifespan of pugs is 12 to 15 years. Pugs sometimes suffer from necrotizing meningoencephalitis, which is a condition that causes inflammation of the brain and meninges. Pugs that are susceptible to the condition experience symptoms within 6 months to 7 years of age.

Pugs that suffer from necrotizing meningoencephalitis typically die, or must be put to sleep within a few months of the disease's onset. Some other conditions that pugs suffer from include canine hip dysplasia, elongated palate, patellar luxation, stenotic nares and Legg-Perthes disease. Other conditions that affect the breed include entropion, keratoconjunctivitis sicca, hemivertebra, demodicosis and distichiasis. Some pugs also suffer from obesity, skin infections, nerve degeneration and allergies.