Jackrabbits survive in the desert by having adaptations that help them to stay cool and avoid the many predators that hunt them. Jackrabbits have exceptional speed, and they sometimes reach 40 miles per hour. This allows them to outrun many potential predators. Additionally, as jackrabbits are herbivores that consume many succulent plants, they are able to obtain most of the water they require through their food.

Jackrabbits have very large ears that help them to radiate heat into the environment, which helps them avoid overheating in the hot desert. Additionally, while they do not dig burrows, jackrabbits rest in the shade of shrubs and trees to help keep their temperature low. Jackrabbits have thinner fur than rabbits and hares that live in cold climates, which also helps them to avoid overheating.

Jackrabbits are actually a type of hare rather than a rabbit. In contrast to true rabbits, which give birth to their young in nests, hares do not construct nests. Instead, they simply give birth to their young in the open. This is possible because young jackrabbits are born fully furred with their eyes open. This allows the newborns to flee danger and protect themselves better than the helpless young of species such as cottontail rabbits, who are born naked with closed eyes.